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The ECRI Institute-Penn Medicine Evidence-based Practice Center (EPC) is one of 13 institutions/organizations designed as an EPC by the Agency for Healthcare Research and Quality (AHRQ). Before aligning with Penn Medicine, ECRI Institute held the EPC designation since the inception of the program in 1997.

Underpinning Clinical Recommendations

The EPC develops evidence reports, systematic reviews, and horizon scans, and assembles and conducts technical expert panel meetings in support of several of the reports. Projects conducted under the EPC Program cover a breadth of health conditions, medical/surgical treatments, health services, and medical technologies.

The reports are used by clinicians, policymakers, health system leaders, and other healthcare professionals as a means to underpin clinical recommendations and inform coverage decisions.

Effective Health Care Program

ECRI Institute was one of the first EPCs to develop a comparative effectiveness review for AHRQ's Effective Health Care Program. This program supports the work performed under Section 1013 of the 2003 Medicare Prescription Drug, Improvement, and Modernization Act. The act authorizes AHRQ to conduct and support research with a focus on outcomes, comparative clinical effectiveness, and appropriateness of devices, prescription medications, diagnostic tests and healthcare services. The reports this program produces are subject to intense public scrutiny.

Download EPC Reports Published by ECRI Institute

Below are some of the more recent reports the ECRI Institute-Penn Medicine EPC has published: