Psilocybin (Synthetic) to Treat Treatment-resistant Depression

Psilocybin (synthetic), being developed as COMP360, is meant to mimic psilocybin, a psychoactive ingredient found in some species of mushroom. When used in combination with psychological support from trained therapists, it might improve patient health outcomes and disrupt the paradigm of depression treatment.

Recent research has found a link between mental health disorders and hyperconnected, dysfunctional, neural networks in the brain. Psilocybin purportedly disrupts those dysfunctional networks and helps restore...