Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure

September 28, 2021 | Technology Forecasts

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Omecamtiv mecarbil (AMG 423) activates cardiac myosin and is intended to increase the duration of cardiac muscle contractility and improve cardiac muscle performance.

The mechanism of action purportedly improves cardiac muscle performance without increasing cellular calcium concentrations that can...

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