USPSTF Issues Final Recommendation on Statin Use for Primary Prevention of Cardiovascular Disease

December 9, 2016 | Strategic Insights for Ambulatory Care


​Statin use is beneficial for some people age 40 to 75 with risk factors for cardiovascular disease, said the U.S. Preventive Services Task Force (USPSTF) in a recommendation released on November 13, 2016. USPSTF recommended "with moderate certainty" initiating low- to moderate-dose statins for adults age 40 to 75 without a history of cardiovascular disease if they have one or more risk factors (dyslipidemia, diabetes, hypertension, or smoking) and a calculated 10-year cardiovascular disease risk of 10% or greater. Evidence was insufficient to make a recommendation for adults age 76 years and older or younger than 40. USPSTF found that statin therapy was not associated with an increased risk of withdrawal from randomized trials due to adverse events, and there were no significant differences in risk of any serious adverse event, according to a November 15, 2016, article inJAMA.

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