Study Identifies Drug-to-Drug Interactions to Inform EHR Medication Decision Support

September 19, 2012 | Risk Management News

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A panel of experts has developed a set of 15 high-severity, clinically significant drug-to-drug interactions to be used for generating medication-related decision support alerts in electronic health records (EHRs), reports a study published in the September 2012 issue of the Journal of the American Medical Informatics Association. From a list of 31 drug-to-drug interactions considered to be high risk, the panel selected 15 based on the consequence of the interaction, severity levels assigned to them across various medication knowledge bases, availability of therapeutic alternatives, monitoring and management options, predisposing factors, and the probability of the interaction based on the strength of evidence available in the literature.

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