InterAtrial Shunt Device (IASD) to Treat Heart Failure

InterAtrial shunt device (IASD) is intended to relieve HF symptoms by reducing elevated left atrial pressure.

A common feature of HF, elevated left atrial pressure causes a backup of blood in the lungs, leading to pulmonary congestion and breathing difficulty. IASD implantation would disrupt management for patients with HF with preserved left ventricular ejection fraction (ie, greater than 40%), which relies on drug therapy prescribed in an outpatient office setting.

To implant the IASD, a physician inserts a specialized catheter into the femoral vein at the groin and threads it up into the right atrium to create an opening in the septum, the wall separating the heart's left and right atrial chambers. The stent-like scaffold is designed...