COVID-19 Clinical Guidelines–Laboratory

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Laboratory biosafety guidance related to coronavirus disease (COVID-19): interim guidance

Date: 2021 Jan 28
Developer: World Health Organization (WHO)

Guideline Focus
Laboratory biosafety related to COVID-19 and the testing of clinical specimens

Patient Population
Patients that meet the case definition of coronavirus disease (COVID-19)

Major Interventions

  • Risk assessment of laboratory processes, implementation toolkit, and referral of specimens to laboratories with appropriate risk control measures
  • Performance of routine laboratory procedures and point of care assays
  • Use of appropriate disinfectants
  • Viral isolation procedures and precautions
  • Considerations for work with infected animals
  • Packaging and shipment of materials

Diagnostic testing for SARS-CoV-2: interim guidance

Date: 2020 Sep 11
Developer: World Health Organization (WHO)

Guideline Focus
Diagnostic testing for COVID-19

Patient Population
Patients with suspected COVID-19, and laboratory personnel

Major Interventions

  • Factors influencing testing decisions
  • Appropriate specimen collection, storage, and transport
  • Laboratory testing options and algorithm, including nucleic acid amplification testing (NAAT) and serologic testing
  • Adherence to reporting requirements and quality assurance

For access to additional guidelines, check out and search the entire ECRI Guidelines Trust® (EGT), a repository of objective, evidence-based clinical practice guidelines.

Return to the ECRI COVID-19 Resource Center