COVID-19 Clinical Guidelines–Critical Care

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COVID-19 clinical management: living guidance

Date: 2021 Jan 25
Developer: World Health Organization (WHO)

Guideline Focus
Management of COVID-19

Patient Population
Adult and pediatric patients with COVID-19

Major Interventions

  • Screening, triage, diagnosis and infection prevention measures
  • Establishment, use, and release from COVID-19 care pathways
  • Symptomatic treatment and monitoring for mild disease
  • Treatment of pneumonia in moderate and severe disease
  • Management of acute respiratory distress syndrome (ARDS) and septic shock, and prevention of complications in critical illness
  • Guidance on adjunctive therapies and treatment of other infections, conditions, and manifestations
  • Care of special populations, including pregnant women, breastfeeding mothers and infants, older persons, and those requiring palliative care or rehabilitation
  • Ethical considerations, reporting of death, and the role of clinical research

SEDAR-SEMICYUC consensus recommendations on the management of haemostasis disorders in severely ill patients with COVID-19 infection

Date: 2020 Aug-Sep
Developer: Spanish Society of Anesthesiology, Resuscitation and Pain Therapeutics (SEDAR)

Guideline Focus
Management of hemostasis disorders and COVID-19

Patient Population
Severely ill patients with COVID-19 and hemostasis disorders

Major Interventions

  • Role and choice of pharmacological and mechanical thromboprophylaxis
  • Dosing considerations and laboratory monitoring
  • Diagnosis of arterial and venous thrombosis
  • Treatment and monitoring of confirmed thrombotic events
  • Considerations for pregnant patients
  • Management of patients on chronic anticoagulant or anti-platelet therapies
  • Management of acute bleeding

Clinical consensus recommendations regarding non-invasive respiratory support in the adult patient with acute respiratory failure secondary to SARS-CoV-2 infection

Date: 2020 May
Developer: Spanish Society of Intensive, Critical Care Medicine and Coronary Units (SEMICYUC)

Guideline Focus
Guidance on non-invasive respiratory support (NIRS) in patients with COVID-19 with acute respiratory failure (ARF)

Patient Population
Adult patients with suspected or confirmed presentation of COVID-19 with ARF

Major Interventions

  • Identification of patients at risk for requiring NIRS
  • Escalation of therapeutic strategies for NIRS
  • Prevention and control of infection in patients receiving NIRS
  • Interventions based on NIRS modality

For access to additional guidelines, check out and search the entire ECRI Guidelines Trust® (EGT), a repository of objective, evidence-based clinical practice guidelines.

Return to the ECRI COVID-19 Resource Center